Expression of interleukin-8 receptors in endometriosis

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Expression of interleukin-8 receptors in endometriosis.

BACKGROUND Although the etiology of endometriosis is not well understood, chemokines and their receptors are believed to play a role in its pathogenesis. Therefore, we aimed to investigate the expression and localization of interleukin-8 (IL-8) receptors CXCR1 and CXCR2 in eutopic and ectopic endometrial tissues of women with endometriosis, and in endometrium of women without endometriosis. M...

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Bachground: Endometriosis is a disease of female genital system, which is defined by the presence of ectopic endometrial tissue outside the uterine cavity. IL-8 is an autocrine growth factor in the endometrium that contributes to the pathogenesis of endometriosis. The aim of this study was to investigate the association between -251T/A polymorphism in the IL-8 gene and endometriosis risk in Ira...

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ژورنال

عنوان ژورنال: Fertility and Sterility

سال: 2004

ISSN: 0015-0282

DOI: 10.1016/j.fertnstert.2004.07.432